Preparation and ocular pharmacokinetics of ganciclovir liposomes
AbstractOphthalmic liposomes of ganciclovir (GCV) were prepared by the reverse phase evaporation method, and their ocular pharmacokinetics in albino rabbits were compared with those obtained after...
View ArticleCharacterization of Multi-Sourced Diclofenac Sodium Extended-Release Tablet...
AbstractPurposeIn this study, a new parameter, volume under response surface (VURS), based on the multiple integrals response surface (MIRS) was applied to establish in vitro-in vivo correlations...
View ArticlePrecisely Defined Polymers for Efficient Gene Delivery
AbstractGene therapy requires successful delivery of therapeutic nucleic acids into target cells; thus, efficient and safe gene delivery carriers are crucial to its success. Although many polymeric...
View ArticlePrecisely Defined Polymers for Efficient Gene Delivery
AbstractGene therapy requires successful delivery of therapeutic nucleic acids into target cells; thus, efficient and safe gene delivery carriers are crucial to its success. Although many polymeric...
View ArticleA DM1-doped porous gold nanoshell system for NIR accelerated redox-responsive...
AbstractBackgroundAlthough many treatments for breast cancer are available, poor tumour targeting limits the effectiveness of most approaches. Consequently, it is difficult to achieve satisfactory...
View ArticleCorrection to: A DM1-doped porous gold nanoshell system for NIR accelerated...
An amendment to this paper has been published and can be accessed via the original article.
View ArticleTime-Programmed Delivery of Sorafenib and Anti-CD47 Antibody via a...
HighlightsA novel injectable double-layer-gel matrix is developed.The hierarchically structured dual lipid gel matrix enables time-programmed drug delivery.Applying a modest dose of sorafenib in...
View ArticleMild photothermal therapy potentiates anti-PD-L1 treatment for...
AbstractOne of the main challenges for immune checkpoint blockade antibodies lies in malignancies with limited T-cell responses or immunologically “cold” tumors. Inspired by the capability of...
View ArticleReactive oxygen species-responsive and Raman-traceable hydrogel combining...
AbstractCombining immune checkpoint blockade (ICB) therapy with photodynamic therapy (PDT) holds great potential in treating immunologically “cold” tumors, but photo-generated reactive oxygen species...
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